Today, I reached a new Milestone in GW2 - I made it to Personal Fractal Level 100. I made a few observations along the way, and hopefully others will find these pointers useful.
1.) Team Build is important. Each member needs to fill one of these Roles - DPS, Alacrity, or Healing. The most successful Teams have 3 DPS, 1 DPS/Alacrity, and 1 Healer.
2.) There are 2 kinds of DPS - straight-up damage, and damage-over-time (Condi...). Both kinds are needed.
3.) A spread-out Team is a dead Team. Everyone needs to stay close to benefit from applied Boons, Heals, Alacrity, and Condi clearing. Of course, there are times when you need to spread out a bit too...
4.) Use the Large Mists Potions - Mobility, Offense, and Defense. You can also use Tear of Alba to gain an extra 10 AR if you need it. Food and Utility consumption is also needed - use the right ones to best support your Role.
5.) Make sure you have at least the recommended amount of AR (Agony Resistance). The recommended AR @ Fractal Scale 100 is 150.
6.) Practice makes perfect, and there is something to learn from every run.
If you are not sure if your character is setup right - weapons, armor, runes, sigils, skills - there are Websites out there that can help. Snow Crows and MetaBattle Wiki are two very useful sites.
~Marcovius